Table 1 Binding Free Energies (BFEs, kcal/mol) for KS and KSDS tetramer binding to the CRDs of the given galectins in orientations 1 and 2.

From: Structural insight into the binding of human galectins to corneal keratan sulfate, its desulfated form and related saccharides

 

Orientation 1

Orientation 2

KS

KSDS

KS

KSDS

Gal-1

− 13 ± 6

− 7 ± 7

− 21 ± 8

− 16 ± 4

Gal-3

− 26 ± 6

ND

− 39 ± 13

− 25 ± 5

Gal-7

− 22 ± 13

− 16 ± 5

− 25 ± 15

− 19 ± 8

Gal-9N

− 30 ± 7

− 12 ± 7

− 34 ± 13

− 18 ± 7

Gal-9C

− 27 ± 8

− 19 ± 4

− 28 ± 9

− 22 ± 6

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