Figure 2
Single nucleotide variants (SNV) frequencies in paired sequencing replicates. (A) Frequency of individual SNVs at passage cycle P0 in two paired sequencing replicates obtained from independent reverse transcription (RT) reactions. The R2 value for variant frequencies between each paired replicate was determined by least-squares regression. (B) Histogram showing the distribution of R2 values between paired replicates at all time points sampled during the passaging experiment.
