Table 1 Dim flash response sensitivity and kinetics parameters.

From: Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca2+ uptake in photoreceptor mitochondria

 

Rmax (μV)

I1/2 (phot/µm2)

SfD (µV/phot/µm2)

tp (ms)

tint (ms)

Ï„rec (ms)

Io* (phot/µm2/s)

n*

Control (N = 8)

508 ± 79

101 ± 8

0.014 ± 0.001

136 ± 5

359 ± 16

65 ± 4

116 ± 17

0.61 ± 0.06

Rod Mcu-/- (N = 8)

605 ± 67

100 ± 18

0.015 ± 0.001

141 ± 6

331 ± 18

65 ± 3

194 ± 37

0.69 ± 0.04

p value

0.36

0.94

0.63

0.50

0.28

0.96

0.08

0.3

  1. Rmax saturated response amplitude measured at the plateau, I1/2 intensity required to produce half of the saturated response, SfD dark adapted sensitivity, tp time to peak of a dim flash response, tint integration time of the response, Ï„rec recovery time constant during response shut off, Io intensity required to decay the sensitivity to one half.
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