Table 1 Comparison of patients’ baseline characteristics in the acute kidney injury and non-acute kidney injury group.

From: A retrospective study on the incidence of acute kidney injury and its early prediction using troponin-I in cooled asphyxiated neonates

 

AKI (n = 23)

Non-AKI (n = 43)

p value

Demographic data

GA (weeks)

37 [37–38]

39 [37–40]

0.006

BBW (g)

2,865 [2399–3393]

2,969 [2705–3281]

0.500

Gender (male)

12(52%)

23(53%)

0.862

Apgar score at 1′

1 [0–5]

2 [0–4]

0.670

Apgar score at 5′

4 [1–6]

4 [2–6]

0.350

CPR at birth, n (%)

15 (65%)

26 (60%)

0.542

Outborn, n (%)

20 (87%)

34 (79%)

0.176

Laboratory data

ABG (first)

 pH

7.01 [6.88–7.18]

7.16 [7.05–7.27]

0.120

 PCO2, mmHg

32.0 [21.4–46.6]

30.5 [20.1–39.9]

0.791

 PaO2, mmHg

84.9 [64.5–156.2]

108.5 [75.4–146.9]

0.931

 HCO3, mm/l

7.9 [4.8–12.6]

11.1 [7.27–14.9]

0.181

Hemoglobin, g/dl

11.8 ± 5.2

15.7 ± 3.5

0.012

Lactate (before TH), mg/dl

171.1[11.9–318.4]

81.4[14.6–255.4]

0.013

Lactate (after TH), mg/dl

31.4 [18.7–77.6]

15.1 [11.5–28.4]

0.030

Troponin-I (before TH), ng/ml

0.34 [0.18–1.20]

0.14 [0.07–0.41]

0.600

Troponin-I (after TH), ng/ml

0.47 [0.17–1.86]

0.07 [0.04–0.16]

 < 0.001

CPK, U/l

1771 [905–3818]

1,458 [779–2345]

0.299

CK-BB, %

12.40 [4.20–35.70]

11.20 [3.45–26.30]

0.817

CK-MB, %

4.10 [2.65–6.35]

4.26 [3.02–5.57]

0.861

CK-MM, %

76.90 [59.25–91.00]

81.85 [67.32–91.80]

0.445

Medications

Inotropes, n (%)

20 (87%)

42 (97%)

0.460

Aminoglycosides, n (%)

6 (26%)

16 (37%)

0.460

  1. AKI acute kidney injury, GA gestational age, BBW birth body weight, CPR cardiopulmonary resuscitation, ABG arterial blood gas, TH therapeutic hypothermia, CPK creatine phosphokinase, CK-BB creatine kinase brain band, CK-MB creatine kinase myocardial band, CK-MM creatine kinase muscle type.
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