Figure 3
From: Structural polymorphisms in fibrillar aggregates associated with exfoliation syndrome

Electron micrographs of XFS fibrils from the surface of lens capsule XFS-M1. (a) Electron micrographs of negatively stained (using 2% UA), isolated XFS deposits from the lens capsule of a 72-year-old male patient (M1) being in moderate stages of XFS at the time of surgery. Arrows in (a) indicate helical twist regions (scale bars = 50 nm). (b) First panel: a representative 2D class average of the two protofilament fibril segments after image processing. One and two protofilament is designated by white arrowheads and arrows, respectively (scale bar = 10 nm). Second panel: a schematic illustration of the 2D class average image.