Figure 4
From: Structural polymorphisms in fibrillar aggregates associated with exfoliation syndrome
Electron micrographs of XFS fibrils from the surface of lens capsule XFS-M2. (a) Electronmicrographs of negatively stained (using 2% UA), isolated XFS deposits from a lens capsule of a 66-year-old male patient (M2) being in moderate stages of XFS at the time of surgery. Arrows in (a) indicate helical twist regions (scale bars = 50 nm). (b) First panel: a representative 2D class average of the fibril segments after image processing (scale bar = 10 nm). White arrows indicate the density of the fibril in the 2D class average image suggesting it is consist of one protofilament only. Second panel: a schematic illustration of the 2D class average.
