Table 1 Subject characteristics in healthy and periodontitis/gingivitis groups.

From: Unculturable and culturable periodontal-related bacteria are associated with periodontal inflammation during pregnancy and with preterm low birth weight delivery

 

H (n = 20)

PG (n = 70)

P-value

Age

28.8 ± 2.9

29.1 ± 4.4

NS

Primiparity (%)

90.0 (18/20)

77.1 (54/70)

NS

Alcohol consumption history (%)

5.0 (1/20)

4.3 (3/70)

NS

Smoking history (%)

0

0

NS

Oral hygiene behavior

Tooth brushing frequency/day

2.2 ± 0.5

2.1 ± 0.4

NS

Duration of tooth brushing (min)

2.7 ± 1.3

2.3 ± 0.9*

0.03

Dental floss or interproximal brush utilization (yes %)

25.0 (5/20)

20.0 (14/70)

NS

Mouth rinse utilization (yes %)

35.0 (7/20)

32.9 (23/70)

NS

Education and socio-economic characteristics

Education ≥ 12 years (yes %)

90.0 (18/20)

78.6 (55/70)

NS

Income ≥ local average salary (yes %)

80.0 (16/20)

62.9 (44/70)

NS

Health insurance (yes %)

60.0 (12/20)

62.9 (44/70)

NS

Periodontal clinical parameters

Mean PPD (mm)

1.8 (1.7 2.0)

2.6 (2.3 2.9)*

 < 0.0001

Mean CAL (mm)

1.8 (1.7 2.1)

2.6 (2.3 3.0)*

 < 0.0001

PPD ≥ 3 mm %

13.1 (9.8 20.1)

52.1 (36.3 64.3)*

 < 0.0001

PPD ≥ 4 mm %

0.6 (0 2.23)

11.9 (6.5 21.9)*

 < 0.0001

PPD ≥ 5 mm %

0

2.1 (0.6 5.7)*

 < 0.0001

BOP %

12.5 (7.5 19.4)

53.6 (41.1 73.7)*

 < 0.0001

Birth outcomes

Birth weeks

39.0 ± 1.5

39.0 ± 1.5

NS

Birth weight (g)

3241.2 ± 456.6

3155.9 ± 457.6

NS

Caesarean section (%)

65.0 (13/20)

48.6 (34/70)

NS

PB (%)

5.0 (1/20)

8.6 (6/70)

NS

SGA (%)

10.0 (2/20)

18.6 (13/70)

NS

Systemic inflammatory mediator

hs-CRP (μg/mL)

3.5 (1.1 9.9)

5.0 (2.7 7.2)

NS

  1. Parametric continuous variables were tested using an unpaired t-test and are given as means ± standard deviations; nonparametric continuous variables were tested using the Mann–Whitney U-test and are given as medians (quartile).
  2. PG, periodontitis/gingivitis; PB, preterm birth; SGA, small for gestational age; PPD, pocket probing depth; CAL, clinical attachment loss; BOP, bleeding on probing; hs-CRP, high-sensitivity C-reactive protein; NS, not significant.
  3. *Significantly different from the H group (P < 0.05).