Table 3 Clinical characteristics of CMV-IgG+, CMV-IgM+ and CMV-NAT+ in blood from healthy donors. The IgG and IgM antibodies of CMV in the blood samples were measured by ELISA. CMV DNA was detected by quantitative real-time PCR. No significant differences in the positivity rates were detected among sex, age, residence, profession and ethnicity. Of the 2986 positive samples (IgG or IgM), the positive rate of CMV-IgG, CMV-IgM and both CMV-IgG and CMV-IgM was 46.25%, 5.82%, 0.07%, respectively. Decreased CMV DNA was noted in the positive specimens (7.56 × 102 to 3.58 × 103 copies/mL). The positive rate of CMV-IgG was 78.91% in age 45–55 group, it’s higher than other age groups.
From: Metagenomic analysis and identification of emerging pathogens in blood from healthy donors
Category | Columns | Total n | CMV-IgG+ n (%) | CMV-IgM+ n (%) | Total (+) IgG+ or IgM+ n (%) | IgG+ and IgM+ n (%) | Real-time PCR CMV-NAT+ n (%) |
|---|---|---|---|---|---|---|---|
Gender | Male | 3214 | 1215 (37.80) | 244 (7.59) | 1459 (45.40) | 1 (0.03) | 5 (0.16) |
Female | 2520 | 1437 (57.02) | 90 (3.57) | 1527 (60.60) | 3 (0.12) | 16 (0.63) | |
Total | 5734 | 2652 (46.25) | 334 (5.82) | 2986 (52.08) | 4 (0.07) | 21 (0.37) | |
Age | 18–24 | 1461 | 494 (33.81) | 22 (1.51) | 516 (35.32) | 0 | 2 (0.14) |
25–34 | 1708 | 552 (32.32) | 155 (9.07) | 707 (41.39) | 3 (0.18) | 9 (0.53) | |
35–44 | 1432 | 712 (49.72) | 117 (8.17) | 829 (57.89) | 1 (0.07) | 7 (0.49) | |
45–55 | 1133 | 894 (78.91) | 40 (3.53) | 934 (82.44) | 0 | 3 (0.26) | |
Marital status | Married | 2927 | 1791 (61.19) | 132 (4.51) | 1823 (62.28) | 2 (0.07) | 12 (0.41) |
Unmarried | 2604 | 719 (27.61) | 168 (6.45) | 1077 (41.36) | 2 (0.08) | 8 (0.30) | |
Unknown | 203 | 52 (25.62) | 34 (16.75) | 86 (42.36) | 0 | 1 (0.49) | |
Education | Masters degree | 893 | 402 (45.02) | 45 (5.04) | 487 (54.54) | 0 | 2 (0.22) |
Undergraduate | 1416 | 583 (41.17) | 38 (2.68) | 721 (50.92) | 2 (0.14) | 5 (0.35) | |
College Diploma | 1121 | 498 (44.42) | 45 (12.93) | 643 (57.36) | 1 (0.09) | 5 (0.45) | |
Under high-school | 1198 | 531 (44.32) | 184 (15.36) | 815 (68.03) | 1 (0.09) | 6 (0.50) | |
Unknown | 1106 | 638 (57.68) | 22 (1.99) | 880 (79.57) | 0 | 3 (0.27) |
