Figure 2
From: Detection of genomic alterations in breast cancer with circulating tumour DNA sequencing
Concordance of variants identified by cfDNA and tumour sequencing. A set of 51 variants for which cfDNA, primary and metastatic tumour sequencing coverage was adequate was identified. VAFs of the variants in each sample type are shown, with plasma cfDNA variants shown on a log-scale. (a) Samples which only had a single variant in this set. (b) Samples with multiple variants in this set. Samples are ordered as in Table 2. (c) CONTRA results for CNV calling for plasma cfDNA, primary and metastatic tumour sites.
