Table 1 Clinicopathologic characteristics of study cohort.
From: Detection of genomic alterations in breast cancer with circulating tumour DNA sequencing
Characteristic | Number (n = 35) |
|---|---|
Median age at study entry, in years | 50 (36–75) |
Ethnicity | |
Chinese | 23 (65.7%) |
Malay | 9 (25.7%) |
Indian | 1 (2.9%) |
Others | 2 (5.7%) |
Subtype | |
HR+/HER2- | 18 (51.4%) |
HER2+ (regardless of HR) | 14 (40.0%) |
TNBC | 3 (8.6%) |
Stage | |
II | 2 (5.7%) |
III | 3 (8.6%) |
IV (all relapsed after prior non-metastatic diagnosis) | 30 (85.7%) |
Number of prior systemic therapies (including non-metastatic) | |
0 | 5 (14.3%) |
1 or more | 30 (85.7%) |
Volume of Disease | |
Low | 10 (28.6%) |
Moderate | 14 (40.0%) |
High | 11 (31.4%) |
Serum CA15-3 levels | |
Not raised | 15 (42.9%) |
Raised | 18 (51.4%) |
Not available | 2 (5.7%) |
