Table 2 Sub-cellular localization of individual mature frataxin proteoforms in mouse liver (n = 2).
From: Extra-mitochondrial mouse frataxin and its implications for mouse models of Friedreich’s ataxia
Fratax in proteoform localization | LGT (N) amount | N-1 (GTL) amount | Total frataxin (ng/mg tissue) | Ratio GTL/LGT | ||
|---|---|---|---|---|---|---|
ng/mg protein | % | ng/mg protein | % | |||
Nucleus | 1.4 | 29.8 | 3.3 | 70.2 | 4.7 | 2.4 |
Mitochondria | 0.4 | 36.4 | 0.7 | 36.6 | 1.1 | 1.8 |
Cytosol | 0.5 | 4.0 | 11.9 | 96.0 | 12.4 | 23.8 |
