Table 3 Association between significant SNPs and clinical variables in cases.

From: The effects of common variants in MDM2 and GNRH2 genes on the risk and survival of osteosarcoma in Han populations from Northwest China

 

rs1690916

χ2a

P

rs3761243

χ2

P

AA

AG

GG

CC

AC

AA

Tumor location, N (%)

Axial

1

40

73

  

39

55

20

  

Long

12

145

325

–

0.40

129

231

122

4.15

0.13

Pathological fracture, N (%)

Yes

2

32

72

  

63

31

12

  

No

11

153

326

–

0.97

105

255

130

62.56

2.61 × 10–14

Metastasis, N (%)

Yes

2

20

56

  

76

1

1

  

No

11

165

342

–

0.57

92

285

141

–

 < 2.2 × 10–16

Enneking stages, N (%)

I

4

28

40

  

2

2

68

  

II

7

137

302

  

90

283

73

  

III

2

20

56

–

0.06

76

1

1

–

 < 2.2 × 10–16

  1. aFisher exact tests were performed for sparse data.
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