Figure 1 | Scientific Reports

Figure 1

From: Base-resolution methylomes of gliomas bearing histone H3.3 mutations reveal a G34 mutant-specific signature shared with bone tumors

Figure 1

Global methylation levels of gliomas and normal brain tissue. (a) Box plots of mean CpG methylation levels. Data on all CpGs, those in CGIs, and those in non-CGI regions are shown for the three glioma subgroups and the normal brain tissue (*p < 0.05; **p < 0.01; ***p < 0.001; n.s., not significant). G34R, N = 4; K27M, N = 13; WT, N = 8; Normal, N = 8. (b) Violin plots of CpG methylation levels in promoters, gene bodies, and CGIs. Mean methylation levels are calculated for non-overlapping 1-Mb sliding windows.

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