Figure 9 | Scientific Reports

Figure 9

From: In silico analysis and in vivo assessment of a novel epitope-based vaccine candidate against uropathogenic Escherichia coli

Figure 9

Results of bladder challenge against UPEC. On days 48 and 180 after the first vaccination, the bladders of mice (n = 5 for each time) were infected with E. coli CFT073. Seven days post challenge, the loads of UPEC were determined in the bladders (A1: day 48 and A2: day 180) and kidneys (B1: day 48 and B2: day 180) of the mice. Solid lines indicate median of the colonization levels. Statistical significance of the differences between the mice groups were determined by Kruskal–Wallis analysis (Dunn’s multiple comparison test) and are shown in between brackets with asterisks or P values. The single asterisk shows statistical significance of control mice over vaccine combinations (p < 0.05). Double asterisks indicate statistical significance of control mice over vaccine formulations (p < 0.01).

Back to article page