Table 2 Mean ± standard deviation of shear wave velocities, obtained by ARFI elastography, values of complete blood count and serum biomarkers between BOAS affected and healthy dogs.

From: Liver and spleen elastography of dogs affected by brachycephalic obstructive airway syndrome and its correlation with clinical biomarkers

 

BOAS signs

p-value*

BOAS affected

Healthy

SWV m/s (± DP)

SpleenSWV

2.47 ± 0.40

2.41 ± 0.45

0.559

LiverMLSWV

1.57 ± 0.37

1.10 ± 0.28

< 0.001***

LiverLLSWV

1.54 ± 0.50

1.03 ± 0.22

< 0.001***

LiverLRSWV

1.23 ± 0.28

0.85 ± 0.23

< 0.001***

LiverCLSWV

1.28 ± 0.42

0.85 ± 0.21

< 0.001***

Complete blood count

RBC (μL)

6,878,919 ± 538,294

7,233,939 ± 494,848

0.005**

HGB (g/dL)

17.82 ± 1.58

18.26 ± 1.33

0.214

HCT (%)

49.94 ± 4.69

51.73 ± 3.47

0.074

PLT (μL)

438,378 ± 123,741

400,697 ± 146,169

0.252

WBC (μL)

11,103 ± 2907

9019 ± 1991

0.001***

Neutrophil (103/μL)

8113 ± 2358

6164 ± 1647

< 0.001***

Lymphocyte (103/μL)

2001 ± 798

2229 ± 1045

< 0.001***

N/L ratio

5.04 ± 3.70

3.56 ± 2.95

< 0.001***

Basophils (103/μL)

1.7 ± 10.35

2.54 ± 14.62

0.295

Eosinophils (103/μL)

554 ± 413

323 ± 280

< 0.001***

Monocytes (103/μL)

466 ± 408

343 ± 255

< 0.001***

Serum biomarkers

AST(μL)

28.27 ± 10.55

31.43 ± 7.64

0.153

ALT (μL)

29.99 ± 12.00

38.03 ± 13.88

0.012*

TB (mg/dL)

0.21 ± 0.15

0.26 ± 0.13

0.161

DB (mg/dL)

0.10 ± 0.12

0.13 ± 0.12

0.298

Total protein (g/dL)

8.60 ± 1.90

8.02 ± 2.21

0.244

Albumin (g/dL)

3.17 ± 0.82

3.46 ± 0.69

0.110

  1. SWV expressed in meters per second (m/s).
  2. SWV shear wave velocity, BOAS brachycephalic obstructive airway syndrome, LiverMLSWV medial liver lobes, LiverLLSWV left lateral liver lobe, LiverLRSWV right lateral liver lobe, LiverCLSWV caudate lobe, RBC red blood cells, HGB hemoglobin, HCT hematocrit, PLT platelet count, WBC white blood cells, N/L ratio neutrophil-to-lymphocyte ratio, AST aspartate aminotransferase, ALT alanine aminotransferase, TB total bilirubin, DB direct bilirubin.
  3. *p-value obtained by covariance analysis (ANOVA). Significance level was set at *p < 0.05, **p < 0.01, ***p < 0.001.
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