Figure 1
From: Tax1BP1 limits hepatic inflammation and reduces experimental hepatocarcinogenesis
Tax1BP1 expression in different hepatic compartments. Tax1BP1 expression was determined in liver lysates of Tax1BP1+/+ and Tax1BP1−/− mice by Western Blotting using a polyclonal antibody (A). Confocal laser scanning microscopy showing hepatocytes´ autofluorescence (green), Tax1BP1 (red), and CD68 (green) (magnification × 400). Arrows in the cutouts show representative areas of colocalization of the indicated stainings, respectively (B). Quantitative PCR was performed to assess relative Tax1BP1 mRNA expression, normalized to GPDH, in whole liver, hepatocytes, all non-parenchymal cells and Kupffer cells. Relative Tax1BP1 expression is shown in relation to whole liver (C).
