Table 1 Patient background information.
From: Lobar microbleeds are associated with cognitive impairment in patients with lacunar infarction
Total (n = 273) | CMB-positive (n = 73) | CMB-negative (n = 200) | P value | |
|---|---|---|---|---|
Age, year | 72.0 ± 11.2 | 72.2 ± 9.2 | 72.0 ± 11.28 | 0.849 |
Sex (female), n (%) | 95 (34.8) | 19 (26.0) | 76 (38.0) | 0.066 |
Body mass index, kg/m2 | 23.8 ± 3.5 | 23.6 ± 3.1 | 23.8 ± 3.7 | 0.735 |
Education, years | 12.3 ± 2.4 | 12.6 ± 2.4 | 11.5 ± 2.3 | 0.001 |
MMSE score, median (IQR) | 27 (25.5–29) | 27 (24–29) | 27 (26–29) | 0.003 |
Hypertension, n (%) | 206 (75.5) | 64 (87.7) | 142 (71.0) | 0.005 |
Diabetes mellitus, n (%) | 69 (25.3) | 16 (21.9) | 53 (26.5) | 0.441 |
Dyslipidemia, n (%) | 151 (55.3) | 34 (46.6) | 117 (58.5) | 0.079 |
Chronic kidney disease, n (%) | 82 (30.0) | 28 (38.4) | 54 (27.0) | 0.070 |
Current smoker, n (%) | 102 (37.4) | 27 (37.0) | 75 (37.5) | 0.938 |
Habitual drinker, n (%) | 109 (39.9) | 31 (43.1) | 78 (39.0) | 0.547 |
Location of infarction | ||||
Corona radiata, n (%) | 86 (31.5) | 28 (38.4) | 58 (29.0) | 0.141 |
Basal ganglia, n (%) | 19 (7.0) | 5 (6.8) | 14 (7.0) | 0.966 |
Capsulae internae, n (%) | 56 (20.5) | 14 (19.2) | 42 (21.0) | 0.741 |
Thalamus, n (%) | 65 (23.8) | 12 (16.4) | 53 (26.5) | 0.084 |
Brain stem, n (%) | 47 (17.2) | 14 (19.2) | 33 (16.5) | 0.604 |
MRI findings | ||||
DSWMH severe, n (%) | 150 (54.9) | 48 (65.8) | 102 (51.0) | 0.030 |
PVH severe, n (%) | 166 (60.8) | 55 (75.3) | 111 (55.5) | 0.030 |
Medial temporal atrophy (IQR) | 1 (0–2) | 1 (0–2) | 1 (0–2) | 0.353 |
CMBs | ||||
Deep, n (%) | 37 (13.6) | |||
Lobar, n (%) | 12 (4.4) | |||
Mixed, n (%) | 24 (8.8) | |||
