Figure 2 | Scientific Reports

Figure 2

From: Micro-rheological properties of lung homogenates correlate with infection severity in a mouse model of Pseudomonas aeruginosa lung infection

Figure 2

Representative mean squared displacement (MSD) plots as a function of the time scale (τ) of polyethylene glycol-coated polystyrene particles. (a–c) mean squared displacement (MSD) of each individual tracer particle trajectory at different τ in representative lung homogenates of murine Pseudomonas aeruginosa NH57388A lung infection samples. All animals were infected with the same bacterial inoculum but developed different degrees of infection that correlated with low (a), medium (b), and high (c) viscoelasticity. The mean and the median of all individual particles are indicated by the red and blue lines, respectively. (d–f) corresponding distribution of the logMSD at a τ = 0.1 s. See also Fig. S2. Tracer particles had a mean diameter of 218 nm. (g–i) Representative mean squared displacement (MSD) distributions at τ = 0.108 s normalized by the ensemble-average MSD (〈MSD) at τ = 0.108 s. See also Fig. S3.

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