Figure 4 | Scientific Reports

Figure 4

From: Differential reperfusion patterns in retinal vascular plexuses following increase in intraocular pressure an OCT angiography study

Figure 4

Sequential optical coherence tomography angiography (OCTA) Monkey 2. (A–H) shows superficial vascular plexus (SVP), deep capillary plexus (DCP) and choriocapillaris (CC) layers. Panel (A), (I) and (Q) shows pre injections OCTA of SVP, DCP and CC respectively. Intra ocular pressure (IOP) was 99 mmHg at 30 s which dropped to 14 mmHg at 7 min. The progression of flow throughout the layers were similar to Monkey 1, but the delay in reperfusion was more marked in Monkey 2. At 30 s, minimal to no flow was detected within the capillary beds and none in the venules in the SVP (B) as compared to Monkey 1 at the same time point. This difference was even more evident when comparing the DCP between animals where recognizable capillary units were only detected after 3–4 min post-injection (M, N, O). There were more evident areas of persistent flow deficits in the CC at 40-min post-injection (X) as compared to Monkey 1. Defects in perfusion was also most apparent in the DCP (P) compared to the SVP (H) and CC at 40 min.

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