Figure 3

Fiber and acetate supplementation did not rescue cardiac dysfunction in Mst1 mice. Shows cardiac function for wild-type (WT) and transgenic-Mst1 (Mst1) mice on control diet, high fibre diet and acetate supplementation. (A) Maximum pressure as measured by cardiac catheter. (B) Maximum dP/dt as measured by cardiac catheter. (C) Mean arterial pressure as measured by cardiac catheter. (D) Systolic pressure as measured by cardiac catheter and (E) Diastolic pressure as measured by cardiac catheter and (F) End diastolic pressure as measured by cardiac catheter. Error bar shows mean ± SEM. *P < 0.05, **< 0.01 ***< 0.001. n = 5–7/group. 2-way ANOVA used to analyse data.