Figure 3 | Scientific Reports

Figure 3

From: The effect of aldosterone and aldosterone blockade on the progression of chronic kidney disease: a randomized placebo-controlled clinical trial

Figure 3

Annual eGFR change of CKD groups classified by baseline plasma aldosterone concentration in the observational study. (A) The CKD cohort was classified into five quintile groups according to the baseline plasma aldosterone concentration. The annual change of each group was compared among the groups by one-way analysis of variance. The lower table shows the plasma aldosterone range and annual change in eGFR of each group. (B) The CKD cohort was classified into the high aldosterone group (aldosterone ≥ 145 ng/dL) and low aldosterone group (aldosterone < 145 ng/dL). The annual change in each group was compared between the groups by unpaired t-test. Data are expressed as mean ± SEM. CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; SEM, standard error of the mean. *p < 0.05.

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