Figure 5

Line plot showing temporal changes in parameters of the EPL and PBO groups in the intervention study. (A) Systolic blood pressure, (B) serum potassium concentration, (C) plasma aldosterone concentration, (D) plasma active renin concentration, (E) urinary protein excretion, (F) urinary α1-microglobulin excretion, and (G) eGFR in each experimental group. The dotted line represents the data of the PBO group and the dashed line the data of the EPL group. Data are expressed as mean ± SEM. eGFR, estimated glomerular filtration rate; EPL, eplerenone; PBO, placebo; SEM, standard error of the mean. *p < 0.05 vs. the PBO group.