Table 3 Multiple regression analysis for the risk of the rate of change in eGFR in the observational study.

From: The effect of aldosterone and aldosterone blockade on the progression of chronic kidney disease: a randomized placebo-controlled clinical trial

Parameter

β

P value

Age

0.002

0.9821

eGFR, ml/min/1.73 m2

 − 0.125

0.2755

PAC, ng/dL

 − 0.257

0.0118

Serum HDL-cholesterol, mg/dL

 − 0.147

0.1302

Urinary NAG, IU/g creatinine

 − 0.336

0.0497

Urinary β2-microglobulin, mg/g creatinine

 − 0.122

0.2325

Urinary α1-microglobulin, mg/g creatinine

0.227

0.0878

Urinary albumin, mg/g creatinine

 − 0.378

0.4714

Urinary protein, g/g creatinine

0.183

0.4122

  1. Urinary markers are normalized by urinary creatinine concentration. eGFR, estimated glomerular filtration rate; PAC, plasma aldosterone concentration; HDL, high-density lipoprotein; NAG, N-acetyl-β-D-glucosaminidase.
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