Table 3 Incidence rates and hazard ratios of vancomycin compared to all comparators stratified for antibiotic treatment duration.

From: The comparative risk of acute kidney injury of vancomycin relative to other common antibiotics

 

N

Cases

Person timeb

Incidence rateb

95% CI

Crude HR

95% CI

Adjusted HRc

95% CI

< 7 days of treatment

Vancomycina

4347

8

18.25

0.44

0.22–0.88

    

Comparators

23,965

72

100.67

0.72

0.57–0.90

0.61

0.30–1.27

0.49

0.22–1.08

7 to 14 days of treatment

Vancomycina

871

9

3.64

2.47

1.28–4.75

    

Comparators

2845

23

11.88

1,94

1.29–2.91

1.28

0.59–2.76

0.89

0.37–2.12

> 14 days of treatment

Vancomycina

231

5

0.96

5.19

2.16–12.48

    

Comparators

738

12

3.08

3.89

2.21–6.86

1.34

0.47–3.79

0.89

0.26–3.10

  1. 95% CI 95% confidence interval, HR hazard ratio.
  2. aIndex group.
  3. bPer 10 person-years.
  4. cAdjusted for age, gender, medical history, co-medication, type of surgery, main diagnosis;