Figure 1
From: Preferential transcription of the mutated allele in NPM1 mutated acute myeloid leukaemia
Schematic representation of the NPM1 gene and the three main splice variants analysed in this study. Exons are denoted using numbered squares. The location of a TCTG duplication in exon 12 (mutation A) is indicated for variants NPM1.1 and NPM1.2. Coloured arrows adjacent to coding sequences describe regions of primer binding allowing discrimination between each splice variant and wild-type and mutated alleles. The schematic was created using BioRender.
