Table 3 Up-regulated DEGs in diploid and triploid parr compared to smolt. Fold changes (FC) and q values (p adj.) are indicated.

From: Transcriptome sequencing and histology reveal dosage compensation in the liver of triploid pre-smolt Atlantic salmon

Gene/Locus

Description

FC

q

Function

Diploid

pck1

Phosphoenolpyruvate carboxykinase 1

9.6

0.03

Involved in glucogenesis

gnai2

Guanine nucleotide-binding protein G(i) subunit alpha-2

9.0

0.00

Adenylate cyclase-modulating G-proteins coupled receptor pathway

loc106566987

n/d

6.5

0.00

n/d

lpin1

Phosphatidate phosphatase LPIN1-like

6.4

0.00

Lipid metabolism

odc1

Ornithine decarboxylase 1

6.3

0.01

Polyamine biosynthesis

cyp2r1

Vitamin D 25-hydroxylase-like

6.1

0.00

Heme and ion binding, monooxygenase and oxidoreductase activity

cyp7a1

Cholesterol 7-alpha-monooxygenase-like

5.6

0.00

Bile acids biosynthesis, cellular response to glucose stimulus, cholesterol catabolism and homeostasis

4ebp

Eukaryotic translation initiation factor 4E binding protein 3–1

4.9

0.00

Negative regulation of translational initiation

epo

Erythropoietin-like

4.8

0.00

Erythrocyte maturation

ga45b

Growth arrest and DNA damage-inducible protein

4.7

0.00

Regulation of cell cycle and response to stress

Triploid

loc106566987

n/d

6.0

0.00

n/d

c2cd4c

C2 calcium-dependent domain-containing protein 4C-like

5.6

0.00

n/d

cish

Cytokine inducible SH2 containing protein

5.3

0.03

Intracellular signal transduction, protein ubiquitination and others

cdh6

Cadherin-6-like

5.0

0.03

Homophilic cell adhesion via plasma membrane

fkbp5

FK506 binding protein 5

4.9

0.03

Heat shock protein binding

cyp2k1

Cytochrome P450 2K1-like

4.8

0.02

Heme and ion binding and oxidoreductase activity

bhmt

Betaine–homocysteine S-methyltransferase 1-like

4.8

0.03

Methionine biosynthesis

4ebp

Eukaryotic translation initiation factor 4E binding protein 3–1

4.7

0.02

Negative regulation of translational initiation

cyp27b1

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like

4.6

0.04

Heme and ion binding, monooxygenase and oxidation

odc1

Ornithine decarboxylase 1-like

4.5

0.00

Polyamine biosynthesis

  1. n/d: not determined.