Table 1 Baseline characteristics of COVID-19 positive patients in the derivation and validations cohorts.

From: A novel severity score to predict inpatient mortality in COVID-19 patients

Baseline characteristics

Derivation cohort (n = 2355)

Validation cohort (n = 2356)

Age-years, mean (SD)

65.3 (15.9)

61.4 (17.2)

Female sex, n (%)

1256 (53.3)

944 (40.1)

White, n (%)

269 (11.4)

197 (8.4)

African American, n (%)

1011 (42.9)

732 (31.1)

Hispanic, n (%)

837 (35.5)

916 (38.9)

Asian, n (%)

44 (1.9)

77 (3.3)

Body mass index (kg/m2) (IQR)

28.9 (24.8–33.8)

28.1 (24.3–32.3)

Diabetes simple, n (%)

442 (18.8)

244 (10.4)

Diabetes complicated, n (%)

323 (13.7)

172 (7.3)

Congestive heart failure, n (%)

357 (15.2)

184 (7.8)

Myocardial infarction, n (%)

137 (5.8)

64 (2.7)

Chronic pulmonary disease, n (%)

181 (7.7)

84 (3.6)

Temperature (°C), (IQR)

37.1 (36.7–37.7)

37.1 (36.7–37.7)

Oxygen saturation (%), (IQR)

95 (90–98)

95 (90–98)

Mean Arterial Pressure (MAP)-mmHg, (IQR)

86.7 (75.7–95.3)

86.7 (76–96.7)

White Blood Cells (WBC) per mm3, (IQR)

7200 (5300–10,000)

7400 (5400–10,500)

Lymphocytes per mm3, (IQR)

1000 (700–1400)

1000 (700–1500)

Platelets k per mm3, (IQR)

212 (158–276)

211.5 (158–281.5)

Alanine aminotransferase (AST) U/L, (IQR)

25 (15–41)

27 (16–46)

Aspartate aminotransferase (ALT) U/L , (IQR)

37 (24–61)

38 (24–64)

Ferritin µg/L , (IQR)

778 (369–1623)

675 (236–1459)

International normalized ratio (INR), (IQR)

1.1 (1.0–1.2)

1.1 (1.0–1.2)

D-dimer mg/ml, (IQR)

1.24 (0.36–3.16)

1.12 (0.0–2.95)

Creatinine µmol/L, (IQR)

110 (80–190)

102 (76–170)

Blood urea nitrogen (BUN) mg/dL, (IQR)

18 (11–35)

16 (9–32)

Glucose mg/dL, (IQR)

117 (105–167)

116 (91–161)

Sodium mmol/L, (IQR)

137 (134–140)

137 (134–140)

Interleukin-6 (IL-6) pg/ml, (IQR)

40.7 (17.3–88.9)

36.1 (14.6–80.1)

C-Reactive protein (CRP) mg/L, (IQR)

6.1 (0.5–15.9)

7 (1.4–16.2)

Procalcitonin ng/ml, (IQR)

0.2 (0.1–1.0)

0.2 (0.09–0.7)

Troponin ng/ml, (IQR)

0.01 (0.01–0.02)

0.01 (0.01–0.03)

In-hospital mortality, n (%)

621 (26.4)

527 (22.4)

  1. Missing data: Congestive heart failure (2%), Chronic Pulmonary Disease (3%), Oxygen saturation (4%), Temperature (3%), Mean arterial pressure (5%), D-dimer (21%), Platelets (3%), INR (9%), BUN (12%), Creatinine (3%), Sodium (4%), Glucose (29%), AST (5%), ALT (4%), WBC (3%), Lymphocytes (3%), IL-6 (66%), Ferritin (28%), CRP (14%), Procalcitonin (44%), and Troponin (14%).