Table 1 Baseline characteristics of COVID-19 positive patients in the derivation and validations cohorts.
From: A novel severity score to predict inpatient mortality in COVID-19 patients
Baseline characteristics | Derivation cohort (n = 2355) | Validation cohort (n = 2356) |
|---|---|---|
Age-years, mean (SD) | 65.3 (15.9) | 61.4 (17.2) |
Female sex, n (%) | 1256 (53.3) | 944 (40.1) |
White, n (%) | 269 (11.4) | 197 (8.4) |
African American, n (%) | 1011 (42.9) | 732 (31.1) |
Hispanic, n (%) | 837 (35.5) | 916 (38.9) |
Asian, n (%) | 44 (1.9) | 77 (3.3) |
Body mass index (kg/m2) (IQR) | 28.9 (24.8–33.8) | 28.1 (24.3–32.3) |
Diabetes simple, n (%) | 442 (18.8) | 244 (10.4) |
Diabetes complicated, n (%) | 323 (13.7) | 172 (7.3) |
Congestive heart failure, n (%) | 357 (15.2) | 184 (7.8) |
Myocardial infarction, n (%) | 137 (5.8) | 64 (2.7) |
Chronic pulmonary disease, n (%) | 181 (7.7) | 84 (3.6) |
Temperature (°C), (IQR) | 37.1 (36.7–37.7) | 37.1 (36.7–37.7) |
Oxygen saturation (%), (IQR) | 95 (90–98) | 95 (90–98) |
Mean Arterial Pressure (MAP)-mmHg, (IQR) | 86.7 (75.7–95.3) | 86.7 (76–96.7) |
White Blood Cells (WBC) per mm3, (IQR) | 7200 (5300–10,000) | 7400 (5400–10,500) |
Lymphocytes per mm3, (IQR) | 1000 (700–1400) | 1000 (700–1500) |
Platelets k per mm3, (IQR) | 212 (158–276) | 211.5 (158–281.5) |
Alanine aminotransferase (AST) U/L, (IQR) | 25 (15–41) | 27 (16–46) |
Aspartate aminotransferase (ALT) U/L , (IQR) | 37 (24–61) | 38 (24–64) |
Ferritin µg/L , (IQR) | 778 (369–1623) | 675 (236–1459) |
International normalized ratio (INR), (IQR) | 1.1 (1.0–1.2) | 1.1 (1.0–1.2) |
D-dimer mg/ml, (IQR) | 1.24 (0.36–3.16) | 1.12 (0.0–2.95) |
Creatinine µmol/L, (IQR) | 110 (80–190) | 102 (76–170) |
Blood urea nitrogen (BUN) mg/dL, (IQR) | 18 (11–35) | 16 (9–32) |
Glucose mg/dL, (IQR) | 117 (105–167) | 116 (91–161) |
Sodium mmol/L, (IQR) | 137 (134–140) | 137 (134–140) |
Interleukin-6 (IL-6) pg/ml, (IQR) | 40.7 (17.3–88.9) | 36.1 (14.6–80.1) |
C-Reactive protein (CRP) mg/L, (IQR) | 6.1 (0.5–15.9) | 7 (1.4–16.2) |
Procalcitonin ng/ml, (IQR) | 0.2 (0.1–1.0) | 0.2 (0.09–0.7) |
Troponin ng/ml, (IQR) | 0.01 (0.01–0.02) | 0.01 (0.01–0.03) |
In-hospital mortality, n (%) | 621 (26.4) | 527 (22.4) |