Table 2 Univariate analysis of discharged and dead patients with Covid-19 in the derivation cohort.
From: A novel severity score to predict inpatient mortality in COVID-19 patients
Predictors | Discharged (n = 1733) | Died (n = 621) | p value |
|---|---|---|---|
Age-years, mean (SD) | 62.72 (16.1) | 72.55 (13.1) | < 0.001 |
Female sex, n (%) | 962 (55.5) | 294 (47.3) | < 0.001 |
White, n (%) | 188 (10.8) | 81 (13) | 0.139 |
African American, n (%) | 759 (43.8) | 252 (40.6) | |
Hispanic, n (%) | 626 (36.1) | 211 (34) | |
Asian, n (%) | 27 (1.6) | 17 (2.7) | |
Body mass index (kg/m2) (IQR) | 29.1 (25–33.9) | 28.2 (23.6–33.2) | 0.42 |
Diabetes simple, n (%) | 327 (18.9) | 115 (18.5) | 0.852 |
Diabetes complicated, n (%) | 241 (13.9) | 82 (13.2) | 0.666 |
Congestive heart failure, n (%) | 248 (14.3) | 109 (17.6) | 0.053 |
Myocardial infarction, n (%) | 102 (5.9) | 35 (5.6) | 0.822 |
Chronic pulmonary disease, n (%) | 120 (6.9) | 61 (9.8) | 0.02 |
Temperature (°C), (IQR) | 37.06 (36.7–37.67) | 37.17 (36.72–37.8) | 0.001 |
Oxygen saturation (%), (IQR) | 95 (92–98) | 92 (84–96) | < 0.001 |
Mean Arterial Pressure (MAP)-mmHg, (IQR) | 89 (80–96.7) | 72.3 (53.3–88.3) | < 0.001 |
White Blood Cells per mm3, (IQR) | 7 (5.2–9.5) | 8.1 (5.8–11.6) | 0.041 |
Lymphocytes per mm3, (IQR) | 1 (0.7–1.4) | 0.9 (0.6–1.3) | < 0.001 |
Platelets k per mm3, (IQR) | 217 (162–279) | 192 (150–259) | < 0.001 |
Alanine aminotransferase (AST) U/L , (IQR) | 24 (15–39) | 29 (17–44) | 0.028 |
Aspartate aminotransferase (ALT) U/L , (IQR) | 34 (23–55) | 52 (31–82) | < 0.001 |
Ferritin µg/L , (IQR) | 675.5 (316–1476) | 1119 (622–1980) | < 0.001 |
International normalized ratio (INR), (IQR) | 1.1 (1–1.2) | 1.1 (1–1.3) | < 0.001 |
D-dimer mg/ml, (IQR) | 1.09 (0.36–2.51) | 2.19 (0.35–7.0) | < 0.001 |
Creatinine µmol/L, (IQR) | 1.01 (0.8–1.52) | 1.62 (1.03–3.1) | < 0.001 |
Blood urea nitrogen (BUN) mg/dL, (IQR) | 16 (10–28) | 29 (13–58) | < 0.001 |
Glucose mg/dL, (IQR) | 132.5 (110–189) | 155 (121–232) | 0.187 |
Sodium mmol/L , (IQR) | 137 (134–140) | 138 (134–142) | < 0.001 |
Interleukin-6 (IL-6) pg/ml, (IQR) | 29.5 (13.7–61.1) | 87 (42.3–179.4) | < 0.001 |
C-Reactive protein (CRP) mg/L , (IQR) | 5.5 (1.1–13.6) | 13.3 (4.3–23) | < 0.001 |
Procalcitonin ng/ml, (IQR) | 0.2 (0.1–0.5) | 0.9 (0.3–3.6) | < 0.001 |
Troponin ng/ml, (IQR) | 0.01 (0.01–0.01) | 0.02 (0.01–0.08) | < 0.001 |