Figure 2 | Scientific Reports

Figure 2

From: Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites

Figure 2

A single injection of LPS increased immobility time in the forced swim test (A) relative to mice injected with saline only. Latency to first become immobile was not affected (B). In the open field test, both the average distance travelled (C) and time in the centre zone (D) were reduced, suggesting that the LPS injection was also anxiogenic after 24 h. Rearing (E) and immobility time (F) in the open field, other measures of locomotor activity, were not altered after 24 h. Data presented as mean + SEM. *p < 0.05; **p < 0.01.

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