Table 2 Summary of the key aqueous-phase metabolites driving the discrimination between LPS and saline treatment groups, and their direction of change compared to saline.

From: Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites

Key brain metabolites

Hippocampus

(LPS vs Saline)

Frontal cortex

(LPS vs saline)

Alanine

 

↓**

Glutamate

 

↓*

Glutamine

↑**

↑***

N-acetylaspartate

↑**

↑***

Glycerol

 

↑**

Serine

 

↓***

Histidine/Phenylalanine

 

↓**

  1. *p < 0.05; **p < 0.01; ***p < 0.001.