Figure 1 | Scientific Reports

Figure 1

From: Biomimetic microenvironmental preconditioning enhance neuroprotective properties of human mesenchymal stem cells derived from Wharton's Jelly (WJ-MSCs)

Figure 1

Experimental workflow. WJ-MSCs were cultured in 21% O2 and 5% O2 in a special chamber that provides constant oxygen level. After 3D scaffold preparation, WJ-MSCs encapsulated in the hydrogels were kept in the same culture conditions. Scaffold degradation, cell migration, viability, proliferation rate, neural differentiation, cytokine, and growth factors expression, as well as co-culture with organotypic hippocampal slices (OHC), were performed at different time points during 7 days of culture.

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