Table 2 Comparison of tumor regression grades between the two pathologists for the five systems.

From: Objective assessment of tumor regression in post-neoadjuvant therapy resections for pancreatic ductal adenocarcinoma: comparison of multiple tumor regression grading systems

Evans’

Kappa = 0.34, percentage of agreement = 58.8%

I

IIa

IIb

III

IV

I

21

24

0

0

0

IIa

5

26

6

0

0

IIb

0

4

6

0

0

III

0

0

1

3

0

IV

0

0

0

0

1

CAP

Kappa = 0.50, percentage of agreement = 72.2%

0

1

2

3

 

0

1

0

0

0

 

1

0

3

2

0

 

2

0

2

29

15

 

3

0

0

8

37

 

MDA

Kappa = 0.65, percentage of agreement = 95.9%

0

1

2

  

0

1

0

0

  

1

0

3

2

  

2

0

2

89

  

JPS

Kappa = 0.33, percentage of agreement = 55.2%

1a

1b

2

3

4

1a

15

10

0

0

0

1b

11

26

3

0

0

2

2

14

9

0

0

3

0

1

2

3

0

4

0

0

0

0

1

ART

Kappa = 0.60, percentage of agreement = 76.3%

0

1

2

3

4

0

1

0

0

0

0

1

0

7

3

0

0

2

0

0

6

4

4

3

0

0

0

11

7

4

0

0

0

5

49

  1. Vertical columns were evaluated by pathologist 1 and horizontal rows were evaluated by pathologist 2. Bold indicates low-grade regression (as shown in Fig. 3).
  2. CAP, College of American Pathologists; MDA, MD Anderson; JPS, Japanese Pancreas Society; ART, Area of Residual Tumor.
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