Table 4 Clinicopathological characteristics of high- and low-grade regression groups based on ART scores.
High-grade regression group (ART score 0, 1, 2, 3) | Low-grade regression group (ART score 4) | P value | |
|---|---|---|---|
No. of patients | 32 | 65 | |
Age, years | |||
Median (range) | 65 (38–84) | 68 (49–78) | |
≥ 70 (%) | 10 (31%) | 21 (32%) | 0.916 |
Sex, male (%) | 18 (56%) | 46 (71%) | 0.156 |
Tumor location (%) | |||
Head/body and tail | 15 (47%)/17 (53%) | 49 (75%)/16 (25%) | 0.005* |
Preoperative diagnosis (%) | |||
R/BR/LA/M | 8 (25%)/16 (50%)/1 (3%)/7 (22%) | 22 (34%)/35 (54%)/6 (9%)/2 (3%) | 0.027* |
Preoperative treatment (%) | |||
CRT/CT | 17 (53%)/15 (47%) | 25 (38%)/40 (62%) | 0.171 |
Tumor differentiation, n (%) | |||
G1/G2/G3/others | 10 (31%)/13 (41%)/3 (9%)/6 (19%) | 32 (49%)/28 (43%)/4 (6%)/1 (2%) | 0.013* |
Vascular invasion (%) | |||
Negative/positive | 18 (56%)/14 (44%) | 7 (11%)/58 (89%) | < 0.001* |
Perineural invasion (%) | |||
Negative/positive | 15 (47%)/17 (53%) | 8 (12%)/57 (88%) | < 0.001* |
Stage (UICC 8th) (%) | |||
0/IA/IB/IIA | 1 (3%)/14 (44%)/8 (25%)/1(3%) | 0 (0%)/6 (9%)/19 (29%)/5 (8%) | 0.001* |
IIB/III/IV | 5 (16%)/2 (6%)/1(3%) | 24 (37%)/11 (17%)/0 (0%) | |
Negative resection margin, n (%) | 6 (19%)/26(81%) | 14 (22%)/51 (78%) | 0.750 |
