Figure 3 | Scientific Reports

Figure 3

From: Assessment of conbercept therapy for high myopia macular neovascularization by optical coherence tomography angiography

Figure 3

(A,B) Optical coherence tomography (OCT) images of a patient with myopic macular neovascularization (mMNV) before and after receiving conbercept. Central macular thickness (CMT) decreased from 371.43 to 248.98 μm. The hyperreflective signal lesions in the outer layer of the retina shrank and the outer structure tended to normalize. (C,D) Optical coherence tomography angiography (OCTA) images of the patient before and after injection. (C) Presents a large-area, highly organized, interlaced high-flow MNV vascular network. It contains small capillary branches and nourishing blood vessels and is surrounded by a low-signal halo, showing a leafy tree crown or sea fan shape. One month after conbercept treatment, the MNV of (D) shows only nourishing blood vessels with larger diameters, the small blood vessels decreased or even disappeared, the blood vessels intertwined, and the blood flow was significantly reduced. The MNV areas in (C) and (D) are 2.69 and 1.08 mm2, while the blood vessel areas are 0.92 and 0.24 mm2, respectively.

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