Table 1 Characteristics of patients with or without COPD used for gene expression analysis.

From: Genetic regulation of gene expression of MIF family members in lung tissue

 

COPD

Non-COPD

p-value

Number

276

236

 

Age (years)

64 (56–70)

62 (55–69.75)

NS

Male/female (n)

162/114

132/104

NS

Smokers/ex-smokers

84/192

58/178

NS

Pack-years

41.5 (30–57)

38 (25–49)

0.0007

GOLD stage (n)

I

1

–

 

II

197

–

 

III

22

–

 

IV

46

–

 

Not classified

10

–

 

FEV1 (% predicted)

62.17 (53.15–70.43)

94.31 (87.14–105.6)

0.0001

FEV1/FVC (%)

58.33 (50.95–64.06)

75.12 (72.83–78.6)

0.0001

  1. Data are represented as numbers (n) or as median with interquartile range. Differences between groups were tested with Mann–Whitney test for quantitative traits and Chi-square for categorical traits. FEV1 and FVC values were obtained before treatment with a bronchodilator.
  2. NS not significant.
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