Scientific Reports

Table 3 Prevalence of genotypes and alleles of other PRM1 and PRM2 polymorphisms.

From: Evaluation of the association between polymorphisms of PRM1 and PRM2 and the risk of male infertility: a systematic review, meta-analysis, and meta-regression

First author, publication year	PRM1 polymorphism	Case			Control			Case		Control
First author, publication year	PRM1 polymorphism	GG	GA	AA	GG	GA	AA	G	A	G	A
Aoki, 2006²⁵	rs35262993	189	3	0	94	2	0	381	3	190	2
Ravel, 2007²⁶	rs35262993	111	0	0	281	0	0	222	0	562	0
Imken, 2009²⁸	rs35262993	133	2	0	155	5	0	315	5	271	2
Tuttelmann, 2010²⁹	rs35262993	167	4	0	75	2	0	338	4	152	2
Grassetti, 2012³¹	rs35262993	109	1	0	53	0	0	106	1	119	0
He, 2012³²	rs35262993	292	1	0	373	1	0	585	1	747	1

First author, publication year	PRM1 polymorphism	CC	CT	TT	CC	CT	TT	C	T	C	T
Jodar, 2011a²³	rs140477029	155	1	0	102	0	0	311	1	204	0
Dehghanpour, 2019³⁹	rs140477029	65	0	0	65	0	0	130	0	130	0

First author, publication year	PRM1 polymorphism	GG	GT	TT	GG	GT	TT	G	T	G	T
Aoki, 2006²⁵	rs35576928	189	3	0	94	2	0	381	3	190	2
Ravel, 2007²⁶	rs35576928	111	0	0	278	3	0	222	0	559	3
Tuttelmann, 2010²⁹	rs35576928	167	4	0	75	2	0	338	4	152	2
Jodar, 2011a²³	rs35576928	155	1	0	102	0	0	311	1	204	0
Jodar, 2011b²³	rs35576928	52	1	0	49	1	0	104	1	99	1
Grassetti, 2012³¹	rs35576928	110	0	0	52	1	0	220	0	105	1
He, 2012³²	rs35576928	328	45	0	256	47	0	701	45	559	47
Aydos, 2018³⁷	rs35576928	100	0	0	100	0	0	200	0	200	0
Nabi, 2018³⁸	rs35576928	92	0	0	87	0	0	182	0	174	0
Zeyadi, 2019²²	rs35576928	9	6	0	9	1	0	24	0	19	1
Dehghanpour, 2019³⁹	rs35576928	65	0	0	65	0	0	130	0	130	0

First author, publication year	PRM1 polymorphism	GG	GC	CC	GG	GC	CC	G	C	G	C
Ravel, 2007²⁶	rs193922261	111	0	0	281	0	0	222	0	562	0
Imken, 2009²⁸	rs193922261	134	1	0	160	0	0	269	1	320	0

First author, publication year	PRM2 polymorphism	CC	CT	TT	CC	CT	TT	C	T	C	T
Siasi, 2012³³	rs779337774	100	0	0	100	0	0	200	0	200	0
Aydos, 2018³⁷	rs779337774	98	2	0	100	0	0	198	2	200	0
Nabi, 2018³⁸	rs779337774	92	0	0	87	0	0	184	0	174	0
Zeyadi, 2019²²	rs779337774	33	3	4	9	1	0	69	11	19	1

First author, publication year	PRM2 polymorphism	GG	GA	AA	GG	GA	AA	G	A	G	A
Nabi, 2018³⁸	rs545828790	92	0	0	84	3	0	184	0	171	3
Dehghanpour, 2019³⁹	rs545828790	65	0	0	65	0	0	130	0	130	0

First author, publication year	PRM2 polymorphism	GG	GC	CC	GG	GC	CC	G	C	G	C
Grassetti, 2012³¹	rs201933708	110	0	0	52	1	0	220	0	105	1
Nabi, 2018³⁸	rs201933708	92	0	0	85	2	0	184	0	172	2
Dehghanpour, 2019³⁹	rs201933708	65	0	0	61	4	0	130	0	126	4

First author, publication year	PRM2 polymorphism	CC	CT	TT	CC	CT	TT	C	T	C	T
Nabi, 2018³⁸	rs115686767	92	0	0	85	2	0	184	0	172	2
Dehghanpour, 2019³⁹	rs115686767	65	0	0	61	4	0	130	0	126	4
Aoki, 2006²⁵	rs200072135	191	1	0	95	1	0	383	1	191	1
Imken, 2009²⁸	rs200072135	135	0	0	159	1	0	170	0	319	1
Jodar, 2011a²³	rs200072135	111	0	0	49	1	0	222	0	99	1

The study of Jodar et al.¹⁷ included two studies.

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