Table 6 Sensitivity analysis at the studies without deviation of HWE in the controls.

From: Evaluation of the association between polymorphisms of PRM1 and PRM2 and the risk of male infertility: a systematic review, meta-analysis, and meta-regression

Polymorphism (number of studies)

Allele

Homozygote

Heterozygous

Recessive

Dominant

OR (95% CI), P, I2, Ph

OR (95% CI), P, I2, Ph

OR (95% CI), P, I2, Ph

OR (95% CI), P, I2, Ph

OR (95% CI), P, I2, Ph

PRM1 rs737008 (11)

0.96 (0.82, 1.14), 0.66, 51, 0.03

1.11 (0.86, 1.42), 0.42, 27, 0.19

0.95 (0.79, 1.14), 0.57, 43, 0.06

0.96 (0.81, 1.14), 0.65, 47, 0.04

1.07 (0.89, 1.27), 0.48, 16, 0.29

PRM2 rs1646022 (2)

1.20 (0.96, 1.48), 0.10, 0, 0.92

0.96 (0.59, 1.56), 0.87, 0, 0.67

1.05 (0.61, 1.80), 0.87, 67, 0.05

1.04 (0.63, 1.73), 0.88, 66, 0.05

0.98 (0.62, 1.56), 0.93, 0, 0.94

PRM2 rs2070923 (4)

0.94 (0.77, 1.14), 0.53, 12, 0.33

0.88 (0.58, 1.31), 0.52, 31, 0.22

0.80 (0.61, 1.06), 0.12, 11, 0.34

0.82 (0.63, 1.06), 0.12, 47, 0.13

0.97 (0.67, 1.41), 0.87, 0, 0.52

  1. Allele: A vs. C, homozygous: AA vs. CC, heterozygous: AG vs. CC, recessive: AA + CA vs. CC, and dominant: AA vs. CA + CC, for PRM1 rs737008, and PRM2 rs2070923 polymorphisms. Allele: C vs. G, homozygous: CC vs. GG, heterozygous: GC vs. GG, recessive: CC + GC vs. GG, and dominant: CC vs. GC + GG, for PRM2 rs1646022 polymorphism.
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