Figure 4
From: Recruitment of parvalbumin and somatostatin interneuron inputs to adult born dentate granule neurons
Running scales PV-inputs to abDGCs. (a) Timeline of voluntary wheel running experiments. (b) Representative traces show optoIPSCs recorded in PV-ChR2 control mice or runners. Blue line indicates 5 ms light pulse. (c) Percent of recorded cells with an optoIPSC response to activation of PV interneurons. (d) Average optoIPSC amplitude in controls and runners at each timepoint. (e) Representative traces show aIPSCs 500 ms trace in PV-ChR2 controls and runners. (f) Average amplitude of aIPSCs in abDGCs in PV-ChR2 controls and runners (Error bars represent SEM. *p < 0.05, **p < 0.01, ***p < 0.001, Mann–Whitney U).
