Figure 5 | Scientific Reports

Figure 5

From: Clinical and functional analyses of AIPL1 variants reveal mechanisms of pathogenicity linked to different forms of retinal degeneration

Figure 5

Expression of AIPL1 variants. Western blotting analysis of wild-type (w/t) AIPL1 and the indicated AIPL1 variants. The proteins were resolved by SDS-PAGE on a 12% gel. (a) The anti-myc antibody recognizes the myc tag fused to the N-terminus of AIPL1. (b) The anti-AIPL1 antibody is directed against a C-terminal AIPL1 epitope1. GAPDH was detected as a loading control. *Demarcates an in silico designed AIPL1 variant not found in patients and not associated with disease.

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