Figure 4

Stability and refolding of dimeric proteins (a) Thermal stability of original dimer, PROSS6 mutation dimer and most stable selection/PROSS6 dimer, determined by variable temperature CD spectroscopy. Shown as fraction unfolded. (b, c, d) Refolding capability of original dimer, PROSS6 mutation dimer and most stable selection/PROSS6 dimer.