Table 3 Expression of B and T cell markers in spleen and lymph nodes.
From: Atherosclerotic plaque vulnerability is increased in mouse model of lupus
Marker (mRNA fold increase) | apoe−/− (n = 10) | apoe−/−.Yaa (n = 8) | p-value |
|---|---|---|---|
Spleen | |||
Th1 | |||
tim3 | 1.13 (1.01–1.65) | 2.51 (1.71–3.47) | 0.010 |
ifnγ | 1.99 (0.55–2.27) | 0.43 (0.32–1.29) | 0.135 |
Treg | |||
foxp3 | 1.21 (0.97–1.40) | 0.87 (0.55–2.41) | 0.756 |
il10 | 1.62 (0.41–1.96) | 0.08 (0.02–0.95) | 0.032 |
Th17 | |||
rorc | 0.97 (0.58–1.34) | 1.36 (0.61–2.63) | 0.494 |
il17 | 0.47 (0.30–1.19) | 3.84 (1.18–10.91) | 0.072 |
Lymph nodes | |||
cd20 | 0.95 (0.92–1.07) | 1.19 (1.01–1.61) | 0.100 |
cd4 | 0.95 (0.81–1.20) | 1.46 (1.19–1.61) | 0.034 |
Th1 | |||
tim3 | 1.01 (0.87–1.09) | 0.87 (0.59–1.32) | 0.689 |
ifnγ | 1.23 (0.71–1.42) | 0.93 (0.61–1.91) | 0.961 |
Th2 | |||
gata3 | 0.93 (0.80–1.40) | 1.05 (0.87–1.46) | 0.625 |
il4 | 0.99 (0.76–1.21) | 0.52 (0.44–0.89) | 0.069 |
Treg | |||
foxp3 | 0.98 (0.71–1.23) | 1.10 (0.97–1.25) | 0.317 |
il10 | 1.06 (0.72–1.40) | 0.54 (0.45–0.73) | 0.083 |
Th17 | |||
rorc | 1.22 (0.73–1.42) | 2.38 (1.40–2.96) | 0.056 |
il17 | 1.12 (0.41–2.39) | 0.69 (0.24–0.82) | 0.130 |
