Figure 1 | Scientific Reports

Figure 1

From: Simulation of atherosclerotic plaque growth using computational biomechanics and patient-specific data

Figure 1

A case example of a coronary artery. (A, B) show the reconstructed arteries (red: lumen, transparent blue: arterial wall) for baseline and follow-up time point, respectively. The lumen stenosis is presented clearly at the follow-up reconstruction (B). (C–F) Distribution of endothelial shear stress, oxidized LDL concentration accumulation in the arterial wall, macrophages concentration and plaque formation. Regions of low ESS present higher accumulation of oxidized LDL and inflammatory molecules. (G, H) Cross-section with plaque formation variable at the baseline (G) and the corresponding follow-up cross section (H). This cross section corresponds at the red dotted line of panel (A). (I, J) Cross-section with plaque formation variable at the baseline (I) and the corresponding follow-up cross section (J), where this cross section is located at the green dotted line of panel (A). (H, J) Cross-sections of increased plaque area and lumen area reduction as found realistically at the reconstructed arteries.

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