Figure 2

Poor ‘browning response’ in irisin lacking mice. (A) Appearance of WT and KO mice; (B, C) representative sections of H&E staining showing adipocytes in intraperitoneal white adipose tissue (iWAT) and interscapular brown adipose tissue (iBAT) (100×) (NIS-Elements Viewer, v4.2.0; https://www.downza.cn/soft/275121.-html); (D) the mean diameter of white adipose cells in iWAT. (E) The sum of the brown adipose area in iBAT (Graphpad Prism, v7.0, https://www.xue51.com/soft/393-2.html). Data are presented as the mean ± SEM, n = 10 per group, **P < 0.01; ***P < 0.001 compared to the WT group.