Figure 4 | Scientific Reports

Figure 4

From: Evaluating the effect of rice (Oryza sativa L.: SRNC05053-6-2) crude extract on psoriasis using in vitro and in vivo models

Figure 4

Epidermal psoriatic cytokine levels in artificial psoriatic human skin and imiquimod-induced psoriasis rat skin. (A) β-defensin (i–v) and CCL-20 (vi–x) immunolabeling of the rat psoriatic epidermis at day 7 post-treatment (magnification, × 400). (i, vi) non-treatment; (ii, vii) 2.5% extract; (iii, viii) 5% extract; (iv, ix) betamethasone; (v, x) calcitriol (D3). Bar graph comparing the expression levels of β-defensin and CCL-20 among the various groups in the artificial psoriatic (xi) and rat psoriatic (xii) skins. (B) Graphs (i–ix) showing correlations among the expression levels of the markers and the histopathological scores.

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