Table 1 Subjects’ characteristics.

From: The role of hyaluronic acid and hyaluronidase-1 in obstructive sleep apnoea

 

Control (n = 40)

OSA (n = 68)

Total (n = 108)

p

Age (years)

51/39–60/

53/47–64/

53/44–62/

0.08

Males (%)

28

72

56

 < 0.01

BMI (kg/m2)

24.75 ± 4.48

31.98 ± 5.97

29.30 ± 6.48

 < 0.01

Hypertension (%)

38

71

58.3

 < 0.01

Diabetes (%)

13

21

17.6

0.29

Dyslipidaemia (%)

30

37

34.3

0.47

Cardiovascular disease (%)

10

15

13

0.48

Chronic cardiac failure (%)

5

12

9

0.24

Cardiac arrythmia (%)

8

21

15.7

0.07

Asthma (%)

10

15

13

0.48

COPD (%)

5

9

7

0.46

Smokers (%)

5

46

30.6

 < 0.01

Pack years

0/0–0/

0/0–10/

0/0–5/

 < 0.01

SBP (mmHg)

120/110–130/

132/124–138/

130/120–136/

 < 0.01

DBP (mmHg)

70/70–80/

80/74–89/

78/70–84/

 < 0.01

CRP (mg/l)

1.47/0.83–2.83/

3.51/1.76–8.27/

2.175/1.15–4.85/

 < 0.01

Glucose (mmol/l)

4.6/4.2–5.2/

5.3/4.9–6.7/

5.1/4.7–6.1/

 < 0.01

Cholesterol (mmol/l)

5.64 ± 1.1

5.45 ± 1.26

5.52 ± 1.20

0.43

HDL-C (mmol/l)

1.61/1.39–1.95/

1.21/0.98–1.33/

1.33/1.14–1.63/

 < 0.01

LDL-C (mmol/l)

3.39 ± 0.98

3.46 ± 1.05

3.44 ± 1.02

0.73

Triglyceride (mmol/l)

1.13/0.88–1.39/

1.67/1.25–2.17/

1.35/1.07–1.96/

 < 0.01

Lipoprotein (a) (mmol/l)

0.25/0.07–0.56/

0.74/0.37–0.99/

0.32/0.12–0.67/

 < 0.01

AHI (1/h)

1.90/0.78–2.70/

18.1/10.3–41.5/

9.25/2.38–28.23/

 < 0.01

ODI (1/h)

0.75/0.20–1.53/

15.9/8.5–33.7/

6.95/1.08–22.38/

 < 0.01

AI (1/h)*

45.11 ± 18.85

48.06 ± 14.57

46.09 ± 17.36

0.65

SPT (min)*

422.5/398.3–439.3/

451.0/404–485/

435.0/403.6–479.1/

0.04

TST (min)*

381.26 ± 45.93

415.32 ± 62.62

402.27 ± 58.81

0.03

TST90% (%)

0.0/0.0–0.8/

3.45/0.53–12.35/

0.7/0.0–6.9/

 < 0.01

MinSatO2 (%)

91/89–93/

83/78–87/

87/81–91/

 < 0.01

ESS

5.5/2.0–6.8/

6/4–9/

6/4–8/

0.02

  1. Data are presented as mean ± standard deviation or median/25–75% percentile/.
  2. AHI apnoea-hypopnoea index, AI arousal index, BMI body mass index, COPD chronic obstructive pulmonary disease, CRP C-reactive protein, DBP diastolic blood pressure, ESS Epworth Sleepiness Scale, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, MinSatO2 minimal oxygen saturation, ODI oxygen desaturation index, SBP systolic blood pressure, SPT sleep period time, TST total sleep time, TST90% total sleep time spent with oxygen saturation below 90%.
  3. *Data available in 23 control subjects and 37 patients with OSA.