Table 4 Results of subgroup analysis.
Outcome of interest | Study | Patient | Effect estimate | Heterogeneity | ||
|---|---|---|---|---|---|---|
OR/WMD = (95%CI) | P | I2% | P | |||
Blumgart anastomosis versus Cattell–Warren anastomosis | ||||||
Primary outcomes | ||||||
POPF(B/C) | 4 | 547 | 0.28 (0.15, 0.52) | < 0.0001 | 41% | 0.17 |
Grade C pancreatic fistula | 2 | 161 | 0.19 (0.03, 1.09) | 0.06 | 48% | 0.17 |
Secondary outcomes | ||||||
Operative time | 2 | 269 | − 57.99 (− 114.22,1.76) | 0.04 | 81% | 0.02 |
Blood loss | 3 | 473 | − 255.09 (− 695.01, − 184.83) | 0.26 | 89% | 0.0002 |
Postoperative hemorrhage | 3 | 473 | 0.29 (0.12,0.72) | 0.008 | 0% | 0.64 |
DGE | 2 | 291 | 0.26 (0.10,0.68) | 0.006 | 0% | 0.9 |
Bile leakage | 3 | 473 | 0.63 (0.21,1.88) | 0.41 | 0% | 0.54 |
Intra-abdominal abscess | 3 | 473 | 0.53 (0.29,0.98) | 0.04 | 2% | 0.36 |
Wound infection | 3 | 473 | 0.44 (0.09,2.21) | 0.32 | 83% | 0.003 |
Morbidity | 2 | 269 | 0.64 (0.27, 1.54) | 0.32 | 64% | 0.09 |
Major morbidity | 2 | 278 | 0.18 (0.01,3.38) | 0.25 | 76% | 0.04 |
Mortality | 3 | 297 | 0.18 (0.05, 0.65) | 0.009 | 0% | 0.97 |
Reoperation | 2 | 210 | 0.16 (0.06, 0.42) | 0.0002 | 0% | 0.9 |
Postoperative hospital stay | 2 | 291 | − 4.81 (− 21.66, 12.05) | 0.58 | 93% | 0.0001 |
Blumgart anastomosis versus Kakita anastomosis | ||||||
Primary outcomes | ||||||
POPF (B/C) | 5 | 1199 | 0.26 (0.09,0.74) | 0.01 | 89% | < 0.00001 |
POPF (B/C) in soft pancreas | 3 | 531 | 0.30 (0.07,1.39) | 0.12 | 90% | < 0.0001 |
Grade C pancreatic fistula | 2 | 442 | 1.11 (0.41,2.99) | 0.84 | 35% | 0.21 |
Secondary outcomes | ||||||
Operative time | 4 | 928 | − 19.08 (− 32.11, − 6.05) | 0.004 | 45% | 0.14 |
Blood loss | 5 | 1199 | − 34.28 (− 62.35, − 6.02) | 0.02 | 0% | 0.63 |
Postoperative hemorrhage | 4 | 959 | 0.58 (0.21,1.60) | 0.29 | 27% | 0.25 |
DGE | 3 | 757 | 0.81 (0.18,3.52) | 0.77 | 72% | 0.03 |
Intra-abdominal abscess | 3 | 757 | 0.36 (0.23,0.56) | < 0.00001 | 0% | 0.89 |
Wound infection | 3 | 757 | 0.44 (0.28,0.69) | 0.004 | 69% | 0.04 |
Morbidity | 2 | 396 | 065 (032,1.35) | 0.25 | 92% | 0.0005 |
Major morbidity | 2 | 517 | 0.72 (0.20,2.65) | 0.63 | 89 | 0.003 |
Mortality | 4 | 928 | 0.91 (0.20,4.08) | 0.9 | 0% | 0.63 |
Reoperation | 4 | 928 | 0.68 (0.22,2.09 | 0.5 | 0% | 0.89 |
Postoperative hospital stay | 5 | 1199 | − 6.44 (− 12.50, − 0.39) | 0.04 | 90% | < 0.00001 |
Blumgart anastomosis versus invagination pancreaticojejunostomy | ||||||
Primary outcomes | ||||||
POPF (B/C) | 2 | 365 | 0.43 (0.21, 0.76) | 0.004 | 0% | 0.67 |
Grade C pancreatic fistula | 2 | 365 | 0.24 (0.06, 0.89) | 0.03 | 0% | 0.86 |
Severe morbidity | 2 | 365 | 0.11 (0.01, 2.46) | 0.17 | 78% | 0.03 |
Secondary outcomes | ||||||
Mortality | 2 | 365 | 0.38 (0.05, 3.12) | 0.37 | 0% | 0.88 |
Reoperation | 2 | 365 | 0.41 (0.18, 0.90) | 0.03 | 0% | 0.57 |
Postoperative hospital stay | 2 | 365 | − 9.80 (− 15.19, − 4.14) | 0.0004 | 80% | 0.003 |
