Figure 3 | Scientific Reports

Figure 3

From: Response of human melanoma cell lines to interferon-beta gene transfer mediated by a modified adenoviral vector

Figure 3

Bystander effect mediated by secreted IFNβ. Cells were transduced with AdRGD-PG-hIFNβ (hIFNβ) or AdRGD-PG-eGFP (GFP) and, the next day, harvested, counted and mixed at the indicated proportions before co-cultivation for 48 h before observation of the hypodiploid cell populations. Also indicated is the percentage of hypodiploid cells observed for each condition. Graphs depict the mean and standard deviation from three independent assays each performed with technical duplicates. Statistical analysis was performed by the One-way ANOVA test and followed by the Tukey’s range test using GraphPad Prism version 5.0 for Windows (GraphPad Software, La Jolla California USA). * p < 0.05.

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