Figure 3 | Scientific Reports

Figure 3

From: Decrease of renal resistance during hypothermic oxygenated machine perfusion is associated with early allograft function in extended criteria donation kidney transplantation

Figure 3

(A) Decrease of renal resistance (RR) during hypothermic oxygenated machine perfusion (HOPE). During the first hour of HOPE, RR changes significantly and reaches a plateau in the later phase of perfusion (Wilcoxon rank sum test). (B) Alterations of relative RR correlate with recipients’ serum creatinine on POD1 (Spearman's rank-order). (C) Development of flow and RR in kidney allografts with primary function (PF, blue) and delayed graft function (DGF, red) during HOPE. Initial flow was lower in the PF group (36 ± 22 ml/min vs. 77 ± 45 ml/min p = 0.040; MWU). (D) Increase of mean flow and decrease of mean RR compared to baseline during HOPE in PF and DGF kidney allografts. Mean alterations of flow and RR were higher in the PF than in the DGF group (RR: 54 ± 16% vs. 25 ± 15% p = 0.013; MWU) *p < 0.05, **p < 0.01 ***p < 0.001.

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