Table 2 Clinical outcome in terms of primary- and secondary endpoints.

From: Decrease of renal resistance during hypothermic oxygenated machine perfusion is associated with early allograft function in extended criteria donation kidney transplantation

 

HOPE (N = 15)

CCS (N = 30)

p-value

DGF

8 (53%)

10 (33%)

0.197

PNF

1 (7%)

0 (0%)

0.333

6-months graft survival (%)

87

100

0.041

6-months DC graft survival (%)

93

100

0.333

ICU stay (days)

3 ± 3

3 ± 4

0.600

CRR 2

− 0.5 ± 0.32

0.13 ± 0.27

0.064

CRR 5

0.11 ± 0.37

0.32 ± 0.26

0.071

eGFR (ml/min) POD 1

11 ± 6

9 ± 4

0.341

eGFR (ml/min) POD 3

13 ± 11

16 ± 13

0.401

eGFR (ml/min) POD 5

13 ± 12

22 ± 16

0.051

eGFR (ml/min) POD 7

14 ± 10

31 ± 15

0.023

eGFR (ml/min) POD 14

22 ± 19

35 ± 18

0.051

eGFR (ml/min) 3 months

29 ± 16

35 ± 19

0.300

eGFR (ml/min) 6 months

32 ± 14

38 ± 17

0.276

Serum Crea (mg/dl) 3 months

2.6 ± 1.4

2.1 ± 1.1

0.253

Serum Crea (mg/dl) 6 months

2.6 ± 1

2.1 ± 1.3

0.352

  1. Values are given as mean ± standard deviation or numbers and (percent).
  2. HOPE, hypothermic oxygenated machine perfusion; CCS, conventional cold storage; DGF, delayed graft function; PNF, primary non-function; DC, death censored; ICU, intensive care unit; Crea, creatinine CRR, creatinine reduction ratio; eGFR, estimated glomerular filtration rate; POD, postoperative day.
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