Figure 6 | Scientific Reports

Figure 6

From: Rapid production of SARS-CoV-2 receptor binding domain (RBD) and spike specific monoclonal antibody CR3022 in Nicotiana benthamiana

Figure 6

Binding of plant-produced mAb CR3022 to RBD protein. The different concentration of plant-produced mAb CR3022, standard human IgG1, and a plant-produced anti-PD1 antibody (as negative control)28 were incubated on plates coated either with the plant-produced SARS-CoV-2 RBD (a) or a commercial CHO-produced RBD (c) and detected with an HRP-conjugated anti-human kappa antibody. In parallel, different dilutions of positive convalescent serum collected from a COVID-19 patient and negative serum were also tested for plant-produced RBD (b) and CHO-produced RBD binding (d). The data are the mean values of triplicates from each concentration or dilution.

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